Detection of 23SrRNA Mutations Strongly Related to Clarithromycin Resistance in Helicobacter pylori Strains Isolated From Patients in the North of Iran
نویسندگان
چکیده
منابع مشابه
detection of 23srrna mutations strongly related to clarithromycin resistance in helicobacter pylori strains isolated from patients in the north of iran
conclusions in the present study, the frequency of clarithromycin resistance was lower than the other studies conducted in iran. resistance frequency in samples isolated from gastric ulcer was higher than other gastric disorders. women and patients aged more than 60 years old showed the most resistance frequency in this study. all resistant strains had the a2143g genotype. results of the 89 h. ...
متن کاملDetection of 23SrRNA Mutations Strongly Related to Clarithromycin Resistance in Helicobacter pylori Strains Isolated From Patients in the North of Iran.
BACKGROUND Helicobacter pylori is curved Gram negative and microaerophilic bacilli that have infected half of the world's population. It is recognized as the causative agent of duodenal ulcer, gastritis peptic ulcer, mucosa-associated lymphoid tissue (MALT) lymphoma and is associated with gastric adenocarcinoma. Resistance to clarithromycin is related to point mutations in 23SrRNA gene on nt 21...
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15 صفحه اولGene mutations of 23S rRNA associated with clarithromycin resistance in Helicobacter pylori strains isolated from Korean patients.
Although resistance of Helicobacter pylori to clarithromycin is a major cause of failure of eradication therapies, little information is available regarding gene mutations of clarithromycin-resistant primary and secondary H. pylori isolates in Korea. In the present study, we examined gene mutations of H. pylori 23S rRNA responsible for resistance to clarithromycin. DNA sequences of the 23S rRNA...
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ژورنال
عنوان ژورنال: Jundishapur Journal of Microbiology
سال: 2016
ISSN: 2008-3645,2008-4161
DOI: 10.5812/jjm.29694